Behind the headlines

Dr David Robert Grimes looks at the eye health issues that are making the news.

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Bioengineered corneas to end reliance on donors

Indian biotech start-up Pandorum claims to have bioengineered a human cornea that will enable scarless healing – and even restore vision. 

Corneal injury and degradation are leading causes of blindness worldwide, and there is a shortage of human corneas available for transplant. Pandorum’s approach uses a hydrogel capable of delivering corneal stem cells to the injured site with the aim of provoking the regeneration of corneal tissue with no resultant scarring. The hydrogel can be directly applied, or 3D printed in the form of corneal lenticules for direct insertion. Pandorum said it had the aim of ultimately removing all dependence on human donor corneas.

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