A study into the damage caused to cells by corneal chemical injury has created a “valuable framework” for researchers keen to understand the multicellular pathogenesis of this type of injury.
A well-recognised and central mediator in corneal neovascularisation is vascular endothelial growth factor (VEGF), but how this works following alkali injury was poorly defined.
The researchers, in China, used mouse corneas to conduct the study, along with single-cell RNA sequencing analysis technology. They found a profoundly rewired VEGF signalling axis, which highlighted potentially important roles for immune cells and limbal stem cells in the signalling networks associated with aberrant angiogenesis (Liu et al, 2026). The study was published in Eye Discovery.
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The College of Optometrists has responded to the GOC consultation on the proposed updated statement on testing of sight and proposed supervision and delegation standards.
The GOC’s findings indicate strong patient satisfaction with eye care services but identifies that registrants have concerns that commercial pressures could potentially impact their ability to deliver the best possible care to patients, as well as affecting their wellbeing.