The wonders of the cornea

8 February 2023
Winter 2023

Brush up your knowledge on one of the most remarkable parts of the eye. Kimi Chaddah explores the cornea’s anatomy, its capacity for healing, and promising research avenues in corneal innervation.

Domains covered

Communication Clinical practice

Corneal innervation is an increasingly exciting avenue in medicine. Examining the innervation of the cornea is beginning to be applied in new ways to understand ocular-specific and systemic diseases, from diabetes to cancer. 

As the body’s most sensitive tissue, the cornea is the most densely innervated part of the body (Yang et al, 2018), receiving innervation solely from nociceptive neurons (which cause us to sense pain after physical damage). Sensory nerve endings in the corneal epithelium have a density around 400 times greater than those in the epidermis of the skin, with approximately 7,000 nociceptors per square millimetre in the cornea (Remington, 2012).

Sign in to continue

Forgotten password?

Not already a member of The College?

Start enjoying the benefits of College membership today. Take a look at what the College can offer you and view our membership categories and rates.

Related further reading

Mike Horler FCOptom presents current treatment strategies for late wet AMD, diabetic oedema and branch vein occlusion.


Thurka Sivapalan MCOptom presents a webinar on OCT in glaucoma diagnosis and management.

The General Optical Council (GOC) has presented a draft response to its call for evidence on the need for change to the Opticians Act (1989) and the consultation on associated GOC policies to its Council.