The CMGs offer information on the diagnosis and management of a range of conditions that present with varying frequency in primary and first contact care.
Recurrent corneal epithelial erosion syndrome is the result of defective adhesion to the basement membrane. The breakdown of corneal epithelium causes unilateral pain, typically when patients awaken. The condition, which may recur over weeks or months, can wake patients during the night, and cause lacrimation, photophobia and blurred vision. It may be due to previous corneal injury or corneal dystrophy. This Clinical Management Guideline outlines the aetiology, signs and symptoms and evidence-based recommendations for diagnosing and treating recurrent corneal epithelial erosion syndrome. It outlines options for non-pharmacological management and pharmacological treatment, and when referral may be appropriate.
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What is recurrent corneal epithelial erosion syndrome?
In this condition the surface skin of the cornea (the clear window of the eye) breaks down, causing sharp pain, watering and sometimes blurred vision. This may happen as the patient wakes after sleep. It may be due to a previous mild injury (corneal abrasion) or to a condition known as a dystrophy in which the surface of the cornea is unusually delicate. The condition may recur over weeks or months.
How is recurrent corneal epithelial erosion syndrome managed?
It is treated by reducing friction between the eye and the eyelids, using lubricating drops and/or ointments, to encourage complete healing of the eye surface. Sometimes other measures are needed, for example a special contact lens applied as a bandage, minor surgery or laser therapy.
Recurrent corneal epithelial erosion syndrome - 21 November 2024 The aetiology section has been amended to include up to date incidence and prevalence data from the UK for recurrent corneal epithelial erosion syndrome (RCES). The predisposing factors section now includes additional examples of common causes of mechanical trauma that may initiate RCES. Under the pharmacological section, the definition of severe cases has been refined including additional treatment options to bring about symptomatic relief.
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