Conjunctivitis medicamentosa (also dermatoconjunctivitis medicamentosa)

Conjunctivitis medicamentosa occurs when topically applied drugs, contact lens solutions, cosmetics, or other environmental/occupational substances come into contact with the surface of the eye, causing irritation or hypersensitivity response. Symptoms include redness, stinging burning, eyelid swelling and blurred vision upon application. These can occur weeks or months after exposure. This Clinical Management Guideline outlines the aetiology, signs and symptoms and evidence-based recommendations for diagnosing conjunctivitis medicamentosa. It provides recommendations for non-pharmacological and pharmacological management, and highlights the need to consult the original prescriber of medications when considering switching to alternatives.

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What is conjunctivitis medicamentosa?

Conjunctivitis medicamentosa is a condition in which a drug applied to the eye as drops or ointment, contact lens solutions or a cosmetic, or some other substance reaching the eye surface, causes an irritative or allergic reaction. Some drugs are more likely than others to create this problem, including some anti-glaucoma agents and antibiotics. It can also be caused by preservatives in the medication. The patient notices redness, stinging or burning and possibly eyelid swelling and/or blurred vision. 

How is conjunctivitis medicamentosa managed?

Once recognised, the remedy involves withdrawing the offending medication and prescribing a substitute if necessary. If a preservative is the cause, it may be possible to obtain drops without preservative.

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Last updated

Conjunctivitis medicamentosa (also Dermatoconjunctivitis medicamentosa)
Version 10
Date of search 14.03.23
Date of revision 27.04.23
Date of publication 12.06.23
Date for review 13.03.25
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