Trauma (chemical)

Chemical trauma to the eye can occur as a result of accidental or deliberate contact with substances including alkalis, acids, detergents, solvents, disinfecting agents and certain contact lens solutions. Symptoms include pain, redness, epiphora and loss of vision. Annual incidence has been reported as 10.7 per 100,000 population. Most patients are males of working age. This Clinical Management Guideline outlines the aetiology, signs and symptoms and evidence-based recommendations for diagnosing and treating chemical eye trauma. It highlights options for non-pharmacological management and pharmacological treatment, and outlines the need for immediate referral of severe cases to hospital eye service or A&E.

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What is chemical trauma of the eye?

A variety of chemicals can damage the eye if they come into accidental or deliberate contact with the eye. These include alkalis, acids, detergents, solvents, certain contact lens solutions and pepper spray or tear gas. Generally, the damage is greatest with alkalis such as ammonia (found in some household cleaners) and sodium hydroxide (present in drain and oven cleaners) as these chemicals pass easily through the outer coat of the eye. Chemical injuries can occur as a result of an assault or a workplace, DIY or household accident. They can also occur in riot control situations.

How is chemical trauma of the eye managed?

It is important to flush the eye immediately with sterile salt solution, or if not available with tap water, and continue to irrigate the eye for at least 20 minutes before seeking medical attention. Contact of chemical substances with the eye can cause a serious injury if not treated quickly.

Chemical injury to the eye usually results in pain, redness and watering of the eye, all of which may be severe. It may also cause loss of vision. The task of the optometrist is to quickly judge the nature and extent of the injury and then, in all but mild cases, to flush the eye with large amounts of irrigating solution in an attempt to wash away the chemical that may have caused the injury.

After this first aid, the optometrist will arrange for the ophthalmologist (specialist eye doctor) to see the patient as soon as possible on the same day. Depending on the severity of the injury, the ophthalmologist may admit the patient to hospital for further intensive treatment.

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Last updated

Trauma (chemical) - 13 March 2026
The aetiology section has been amended to provide an update to the incidence and additional possible causes of chemical injuries to the eye. This section now also includes reference to classification systems that can help describe the severity of ocular chemical trauma. The signs section has been updated to include clinical features that increase the risk of limbal stem cell deficiency. The non-pharmacological management section has been amended to include an updated recommended irrigation procedure to ensure pH restoration and consideration of using of topical anaesthesia to aid irrigation, ocular examination and visual acuity measurement.

Trauma (chemical) - 11 April 2024
The aetiology section has been revised to include the involvement of household cleaning and disinfection products that are typically implicated in chemical trauma involving children. The importance of immediate irrigation is further stressed under the non-pharmacological management section given the impact of time to performing irrigation on prognosis. Additional pharmacological recommendations have been provided to help manage symptoms and signs observed in mild cases.

Version 14
Date of search 11.12.25
Date of revision 22.12.25
Date of publication 13.03.26
Date for review 10.12.27
© The College of Optometrists