Glaucoma (primary open angle) (POAG)

Primary Open Angle Glaucoma (POAG) is a progressive optic neuropathy and one of the most common types of glaucoma commonly seen in people over 40. This Clinical Management Guideline outlines the aetiology, signs and symptoms and evidence-based management options for diagnosing and treating primary open-angle glaucoma. It provides a helpful summary of the pharmacological, laser (SLT) and surgical treatment options.  

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What is primary open angle glaucoma?

Glaucoma is the name given to a group of eye conditions in which the optic nerve is damaged.  The optic nerve transfers visual information from the eye to the brain and, if it is damaged, this can result in sight loss. Primary Open Angle Glaucoma (POAG) is the most common form of glaucoma in the UK, affecting approximately 2% of the UK population aged over 40 years, increasing to 4-5% of those aged over 80 years.  It is more likely to affect people with a family history of the same condition and people of West African ancestry, including those with African-Caribbean ancestry. POAG is a slow developing condition that causes damage to the optic nerve. The condition is not painful and patients may be unaware that they have it until they have started to lose vision. The optometrist examining a patient for POAG, will look for the characteristic appearance of ‘cupping’ of the optic disc (the head of the optic nerve at the back of the eye).  The optic nerve transfers visual information from the eye to the brain and can be examined with various special instruments. On testing the patient’s fields of vision, defects may be found that are typical of glaucoma. The pressure of the fluid inside the eye (known as the intraocular pressure) must be measured as it is usually raised in glaucoma. In a small proportion of patients, however, the pressure is within the normal range.

The eyeball is a sphere kept inflated by fresh clear fluid formed within the eye. This fluid drains away through a fine ring-shaped sieve of tissue, known as the drainage angle (or simply angle), situated within the eye at the edge of the cornea (the clear window of the eye) and from there into the bloodstream. This sieve is not directly visible, but it can be seen through a special contact lens containing a mirror.  In POAG the fluid is unable to escape normally because the meshwork has become blocked. The blockage causes the pressure inside the eye to rise, and in time this can damage the optic nerve, causing loss of visual field and even blindness if the condition is not treated. 

How is primary open angle glaucoma managed?

If your optometrist suspects you have primary open angle glaucoma, they will arrange further tests. If glaucoma is confirmed, you will usually be referred to a hospital eye clinic for ongoing care. Treatment aims to lower the pressure inside your eye. Most people start with pressure-lowering eye drops or a laser treatment. If these do not control the glaucoma well enough, surgery may be recommended. If these treatments do not work well enough, or if the condition is more advanced, surgery may be needed

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Last updated

Glaucoma (primary open angle) (POAG) - 9 September 2026
The name of the condition has been amended to clarify that this clinical management guideline (CMG) deals with primary open angle glaucoma (POAG) as a distinct clinical entity, rather than chronic open angle glaucoma which may also include secondary causes. The predisposing factors section has been updated to include vascular risk factors that are particularly associated with normal tension glaucoma. In the signs section, additional detail on disc haemorrhage and the appropriate use of imaging studies (e.g. OCT, fundus photos) has been provided. Under differential diagnosis, the definition of ocular hypertension has been revised to align with the related CMG. The non-pharmacological management section has been updated to reflect national recommendations on glaucoma referral, monitoring, treatment and pathway design. The management category section now sets out the recommended referral pathways for suspected and confirmed POAG. The possible management section has been revised to clarify the range of interventions available has been revised according to the severity of POAG.

Version 19
Date of search 15.06.26
Date of revision 26.06.26
Date of publication 10.09.26
Date for review 14.06.28
© The College of Optometrists